Tumor Types & Biomarkers
Tumor Types & Biomarkers

Explore clinical guidelines on why, whom and how to test actionable biomarkers in lung, breast, ovarian and prostate cancers.
- Lung Tumor
  
  EGFR
  
  ERBB2 (HER2)
- Breast Tumor
  
  BRCA1/2
  
  ESR1
  
  HER2
  
  PIK3CA/AKT1/PTEN
- Ovarian Tumor
  
  HRD
- Prostate Tumor
  
  HRRm
  
  PTEN
Testing Solutions
Explore Precision Medicine

Explore Precision Medicine

Implement best practices in your workflow and discover how recent advances are optimizing precision medicine.

Realizing the Potential of Precision Medicine

Collaborate across the MDT to address health inequities and optimize testing pathways.
Realizing the Potential of Precision Medicine

Latest Developments in Precision Medicine

Explore recent advances in diagnostic technologies and novel biomarkers to support precision medicine in your practice.
Latest Developments in Precision Medicine
Resources

Resources

Access a range of resources you can apply in your practice.

FAQs

Find answers to frequently asked questions about precision medicine.
FAQs

Find a Testing Lab

Search our directory of major laboratories that perform diagnostic biomarker testing.
Find a Testing Lab

Glossary

Find definitions for the most commonly used terms in precision medicine.
Glossary

Resource Library

Explore our library of videos and downloadable tools to help optimize your practice and inform your patients.
Resource Library

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Our Team

Pathologists

The Ever-Expanding Potential
of Precision Medicine

Supporting pathologists and the broader oncology care team in removing barriers to clinically actionable biomarker testing.

Explore Biomarker Testing Guidelines

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines^®) inform biomarker testing.

Access quick-reference flow charts of National Comprehensive Cancer Network^® (NCCN^®) biomarker testing recommendations by tumor type:

Lung tumor guidelines^a

Breast tumor guidelines

Ovarian tumor guidelines

Prostate tumor guidelines

NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.

^aThis page contains content pertaining to non-small cell lung cancer (NSCLC) only.

NCCN^®, National Comprehensive Cancer Network^®.

The Biomarkers Informing Treatment Options

Many tumors contain actionable biomarkers. Testing unlocks this critical information, helping patients receive the right treatment for their unique cancer.

Select a biomarker below to view available diagnostic prevalence as well as practical information on how to test for them:

Lung Cancer

EGFR ERBB2 (HER2)

Ovarian Cancer

HRD

Breast Cancer

BRCA1/2 ESR1 HER2 PIK3CA/AKT1/PTEN

Prostate Cancer

HRRm, including BRCA1/2PTEN

AKT1, serine/threonine protein kinase 1; BRCA1/2, BReast CAncer susceptibility gene 1/2; EGFR, epidermal growth factor receptor; ERBB2, erb-b2 receptor tyrosine kinase 2; HER2, human epidermal growth factor receptor 2; HRD, homologous recombination deficiency; HRRm, homologous recombination repair gene mutation; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; PTEN, phosphatase and tensin homolog.

How Pathologists Can Help Optimize Precision Medicine

Improve your MDT's biomarker testing approach with reflexive testing, synoptic reporting, and enhanced communication.

Collaborate to improve access to
targeted treatment

Explore how MDT partnership can help improve testing pathways and ensure that the promise of precision medicine is as accessible as possible to all communities.

Realize the potential

Keep up with the pace of precision medicine

Wherever you may be in your biomarker testing journey, stay current on recent technology advances in cancer detection and emerging biomarkers to support precision medicine in your practice.

Discover latest developments

MDT, multidisciplinary team.

Solutions for Common Biomarker Testing Challenges

Find new ways to optimize your testing protocols and address common testing challenges to help ensure that all eligible patients can benefit from the potential of biomarker-based therapies.